WHSC2 anticorps (N-Term)

N° du produit ABIN2788623

Cet anticorps Lapin Polyclonal détecte spécifiquement WHSC2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio) et Saccharomyces cerevisiae.

Aperçu rapide pour WHSC2 anticorps (N-Term) (ABIN2788623)

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WHSC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WHSC2 anticorps

Épitope: N-Term

Séquence: LLRKERGVKL LDISELDMVG AGREAKRRRK TLDAEVVEKP AKEETVVENA

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against WHSC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human NELFA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WHSC2

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Autre désignation: WHSC2

Sujet: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Alias Symbols: WHSC2, NELF-A, P/OKcl.15
Protein Size: 393

Poids moléculaire: 43 kDa

ID gène: 7469

NCBI Accession: NM_005663, NP_005654

UniProt: Q9H3P2

Pathways: Chromatin Binding